Electrochemical synthesis cells

ESA’s new, high-efficiency, high-capacity electrochemical cells make it easy to synthesize significant quantities of difficult-to-obtain metabolites from a variety of parent compounds. Since the user can control the systems’ oxidation capability to generate specific, desired oxidation products, they have wide utility in a variety of metabolite-generation tasks.

We designed two synthesis cells to suit specific application needs. The 5150 cell has high capacity and is preferred for low-potential (<500 mV) oxidation reactions, while the 5125 cell is recommended for high-potential reactions. Although smaller in volume, the 5125 cell minimizes unwanted over-oxidation reactions.

Features and benefits

• Biologically relevant – cells mimic much of the oxidation capabilities of cytochrome P450, a key enzyme family that is responsible for metabolizing most drugs.
• High product yield – cells can generate microgram quantities of product with a single injection of starting compound.
• In-line synthesis capability – cells are integrated into either analytical or semi-preparative HPLC system for easy purification of reaction products.