Metabolomics® System – Unleash the power of the ESA CoulArray to enhance your metabolomics research program

A full understanding of a biological system requires the comprehensive study of the small organic molecules (anti-oxidants, enzyme co-factors, cellular metabolites, vitamins, etc.) responsible for the maintenance of routine physiological functions. Changes in the levels of these molecules caused by disease or external stimuli can play an important role in the development or progression of disease and in adverse drug effects. ESA has combined its unique products and bioanalytical expertise to support critical metabolomic research never-before possible. In recognized for our leadership in this field, in March 2005, we received a National Institutes of Health roadmap grant designed to encourage promising technologies in metabolomics. This grant will help us develop our discovery products further by integrating them with mass spectrometry. Click here to read a news release regarding the grant, or here to learn more about metabolomics.

Compatible with both in vitro and in vivo experimental methods, and supported by the latest in pattern recognition, bioinformatics software, ESA’s Metabolomics® System enables quick and accurate measurement of a wide variety of physiologically relevant molecules:

• Examine either a broad spectrum or specific types of compounds, metabolites, and endogenous compounds
• Simultaneously assess and measure xenobiotics and their effects
• Study patterns of individual markers
• Easily identify and quantitate potential surrogate marker compounds
• Study the multivariant effects of external stimuli on biological systems
• Identify and measure the effects of even small perturbations using in vitro or in vivo biological systems
• Rapidly correlate and recognize "normal," "diseased," and "treated" patterns of molecules
• Easily integrate mass spectrometry for compound identification

To see how ESA’s Metabolomics System develops a metabolomic profile, the key to understanding cellular behavior, click here, or to read more about the informatics behind our Metabolomics System, click here.