Metabolomics® System – unleash the power of the ESA CoulArray to enhance
your metabolomics research program
A full understanding of a biological system requires the comprehensive study
of the small organic molecules (antioxidants, enzyme co-factors, cellular
metabolites, vitamins, etc.) responsible for the maintenance of routine
physiological functions. Changes in the levels of these molecules caused by
disease or external stimuli can play an important role in the development or
progression of disease and in adverse drug effects. ESA has combined its unique
products and bioanalytical expertise to support critical metabolomic research
never-before possible. Recognized for our leadership in this field, in
March 2005, we received a National Institutes of Health roadmap grant designed
to encourage promising technologies in metabolomics. This grant will help us
develop our discovery products further by integrating them with mass
spectrometry. Click here to read a news release regarding the
grant, or to learn more about metabolomics.
Compatible with both in vitro and in vivo experimental
methods and supported by the latest in pattern-recognition software, ESA’s
Metabolomics® System enables quick and accurate measurement of a wide variety of
physiologically relevant small molecules, and allows the researcher to:
- Examine either a broad spectrum or specific types of compounds, metabolites,
and endogenous compounds
- Simultaneously assess and measure xenobiotics and their effects
- Study patterns of individual markers
- Easily identify and quantitate potential surrogate marker compounds
- Study the multivariant effects of external stimuli on biological systems
- Identify and measure the effects of small changes using in vitro or
in vivo biological systems
- Rapidly correlate and recognize "normal," "diseased," and "treated" patterns
of molecules
- Easily integrate mass spectrometry for compound identification
To see how ESA’s Metabolomics System develops a metabolomic profile, the key
to understanding cellular behavior, click here, or to read more about the
informatics behind our Metabolomics System, click .
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