Drug DiscovArray system :: ESA – a Magellan biosciences company
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Drug DiscovArray system – a multi-functional system for pharmaceutical discovery applications

Assessing a compound's inherent chemical properties and pharmacological characteristics using various in vitro and in vivo assays is a crucial step in determining a compound's suitability for drug development. Accurately predicting the fate of a compound once it is administered as a therapeutic remains a significant challenge in any drug-discovery operation.

Using chemistry to better understand biology

For many years, EC systems merely measured the flow of electrons (e-) generated from redox reactions to measure a given analyte. But in the past few years, researchers have begun to understand and exploit the ability of EC systems to perform oxidation/ reduction reactions to mimic and study many important biological processes. It is well known that many key biological and pharmacological properties of compounds have their basis in redox chemistry.

Our customers were looking for an optimal platform to study the important chemical and pharmacological properties of potential drug candidates, and Thermo Scientific has delivered with the DiscovArray – a powerful combination of electrochemical cell and array that can perform all redox applications in a single system. The DiscovArray system represents a major leap forward in drug discovery and development operations:

  • Formats in a single platform for maximum efficiency
  • Ability to perform all EC applications, including traditional EC detection
  • Easy integration into LC or LC-MS systems
  • Simple operation, instrument control, and data-management tools
  • Easy integration with most bioanalytical and data-analysis systems
  • Quick switching between applications with minimal time and effort
  • Easily customized to fit your application needs.
System components
    70-4334 Model 5600A CoulArray Detector, 16 Channel
    70-4340T CoulArray Organizer with Temperature Control
    70-1838 Cable, Dual Channel for Coulochem III with DC Control (Connect one or two single-channel cells 5020/5021(A)/5040/5041/5125/5150 to CoulArray series detector)
    70-5971 High Voltage Ground Decoupler Kit for Coulochem III (for use with ESA 5030/5125/5150 cells and/or MS systems to isolate high voltage from ground)
    5042.0036 LPG-3400BM Quaternary Biocompatible Micro Pump for use with CoulArray®
    70-1838 Cable, Single Channel Cell to CoulArray Series Detector